Alzheimer’s Disease: Causes, Symptoms, and Innovative Treatment Approach
Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by progressive cognitive impairment, disorientation, executive dysfunction, and personality and behavior changes. According to the recent Alzheimer’s Disease International, approximately 55 million people globally are suffering from dementia, with the number expected to reach 139 million by 2050. Alzheimer’s disease accounts for more than half of these cases. Hallmarks of Alzheimer’s disease The two pathological hallmarks of Alzheimer’s disease are amyloid plaques and neurofibrillary tangles (NFTs). Amyloid plaques arise from improper cleavage of the amyloid precursor protein (APP), resulting in aggregates of amyloid-beta (Aβ) monomers that form plaques. Neurofibrillary tangles...
2024.08.08